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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPN14
All Species:
17.88
Human Site:
Y733
Identified Species:
39.33
UniProt:
Q15678
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15678
NP_005392.2
1187
135261
Y733
M
L
R
E
K
M
E
Y
S
A
Q
L
Q
A
A
Chimpanzee
Pan troglodytes
XP_001171329
1187
135241
Y733
M
L
R
E
K
M
E
Y
S
A
Q
L
Q
A
A
Rhesus Macaque
Macaca mulatta
XP_001106167
1187
135194
Y733
V
L
R
E
K
M
E
Y
S
A
Q
L
Q
A
A
Dog
Lupus familis
XP_849236
1187
134903
Y733
V
L
R
E
K
M
G
Y
S
A
Q
L
Q
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q62130
1189
135012
V733
V
P
V
L
R
E
K
V
E
Y
S
A
Q
L
Q
Rat
Rattus norvegicus
Q62728
1175
133393
E739
L
T
A
A
F
S
Q
E
Q
Q
L
N
Y
P
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511302
1193
135259
Y738
A
L
H
E
N
L
E
Y
S
A
Q
L
Q
A
A
Chicken
Gallus gallus
XP_419419
1191
135566
S738
L
H
E
N
M
K
Y
S
A
Q
L
Q
A
A
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001339962
834
94004
L428
S
H
S
M
E
T
V
L
T
S
P
P
A
Y
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
M620
D
Q
V
V
T
I
K
M
R
P
D
R
H
G
R
Sea Urchin
Strong. purpuratus
XP_796215
1318
147575
D744
A
V
P
T
G
Y
E
D
N
L
P
T
P
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.9
95.6
N.A.
91.5
53.7
N.A.
87.9
84.9
N.A.
32.8
N.A.
N.A.
N.A.
24.7
34.5
Protein Similarity:
100
99.7
99.5
97.2
N.A.
95.6
70.7
N.A.
92.1
91.5
N.A.
48.1
N.A.
N.A.
N.A.
42
51.7
P-Site Identity:
100
100
93.3
86.6
N.A.
6.6
0
N.A.
73.3
6.6
N.A.
0
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
26.6
13.3
N.A.
80
20
N.A.
20
N.A.
N.A.
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
10
10
0
0
0
0
10
46
0
10
19
55
46
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
0
0
0
0
0
0
10
0
0
10
0
0
0
10
% D
% Glu:
0
0
10
46
10
10
46
10
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
10
0
0
0
0
0
0
10
0
% G
% His:
0
19
10
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
37
10
19
0
0
0
0
0
0
0
0
% K
% Leu:
19
46
0
10
0
10
0
10
0
10
19
46
0
10
10
% L
% Met:
19
0
0
10
10
37
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
10
0
0
0
10
0
0
10
0
0
0
% N
% Pro:
0
10
10
0
0
0
0
0
0
10
19
10
10
19
0
% P
% Gln:
0
10
0
0
0
0
10
0
10
19
46
10
55
0
19
% Q
% Arg:
0
0
37
0
10
0
0
0
10
0
0
10
0
0
10
% R
% Ser:
10
0
10
0
0
10
0
10
46
10
10
0
0
0
0
% S
% Thr:
0
10
0
10
10
10
0
0
10
0
0
10
0
0
0
% T
% Val:
28
10
19
10
0
0
10
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
10
46
0
10
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _